Diabetic ketoacidosis at the onset of type 1 diabetes is associated with future HbA1c levels

Diabetic ketoacidosis at the onset of type 1 diabetes is associated with future HbA1c levels
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DOI:
10.1007/s00125-013-2850-z
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发表时间:
2013-05-01
期刊:
影响因子:
8.2
通讯作者:
Svensson, J.
Svensson, J.
中科院分区:
医学1区
文献类型:
--
作者:
Fredheim, S.;Johannesen, J.;Svensson, J.

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目的/假设我们研究了糖尿病酮症酸中毒(DKA)在发病时对代谢调节和残余β细胞功能在丹麦1型diabetes.Methods人口的长期影响,这项研究是基于数据DanDiabKids,丹麦国家糖尿病儿童登记。该登记册提供了1996-2009年诊断的1型糖尿病患者的临床和生化数据,然后随访至2012年1月1日。结果研究人群包括2,964名儿童
Aims/hypothesis We investigated the long-term impact of diabetic ketoacidosis (DKA) at onset on metabolic regulation and residual beta cell function in a Danish population with type 1 diabetes.Methods The study is based on data from DanDiabKids, a Danish national diabetes register for children. The register provides clinical and biochemical data on patients with type 1 diabetes diagnosed in 1996-2009 and then followed-up until 1 January 2012. Repeated-measurement models were used as statistical methods.Results The study population comprised 2,964 children