EFFECT OF ANTIHYPERTENSIVE TREATMENT ON THE BEHAVIORAL CONSEQUENCES OF ELEVATED BLOOD-PRESSURE
EFFECT OF ANTIHYPERTENSIVE TREATMENT ON THE BEHAVIORAL CONSEQUENCES OF ELEVATED BLOOD-PRESSURE
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DOI：
10.1161/01.hyp.6.2_pt_1.202
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发表时间：
1984-01-01
期刊：
影响因子：
8.3
通讯作者：
HOSUTT, JA
中科院分区：
文献类型：
--
作者：
MILLER, RE;SHAPIRO, AP;HOSUTT, JA
先前的一项研究表明，轻度高血压患者在几项感觉知觉、认知和精神测试中的表现明显不如匹配的血压正常对照组。为了确定这些缺陷是否可归因于血压升高本身，高血压和对照组被召回进行复查15个月。在最初的测试之后。那些用降压药降低血压的高血压患者表现出明显的行为评分恢复到正常血压受试者的水平。与对照组相比，未接受积极治疗的高血压患者仍然存在缺陷。轻度高血压患者的行为缺陷可能是血压升高对中枢神经系统影响的可逆后果。
It was shown in a prior study that mildly hypertensive patients performed significantly less effectively on several sensory-perceptual, cognitive and psychomotor tests than did matched normotensive controls. To determine whether these deficits are attributable to elevated blood pressure per se, hypertensive and control subjects were recalled for reexamination 15 mo. after the original tests. Those hypertensives in whom blood pressure had been lowered with antihypertensive drugs showed significant restoration of performance scores toward the levels of normotensive subjects. Hypertensives who had not received active treatment remained deficient as compared with controls. Behavioral deficits in mild hypertensive may be reversible consequences of the effects of elevated blood pressure on the CNS.