Paper-like Surface Microstructure Fabricated on a Polymer Surface by Femtosecond Laser Machining
Paper-like Surface Microstructure Fabricated on a Polymer Surface by Femtosecond Laser Machining
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DOI：
10.2116/analsci.34.33
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发表时间：
2018-01
影响因子：
1.6
通讯作者：
K. Goya;Yusuke Fuchiwaki
中科院分区：
文献类型：
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作者：
K. Goya;Yusuke Fuchiwaki
在这项研究中，我们展示了精确控制的流体流动，使用飞秒（FS）激光诱导微结构。刻在聚甲基丙烯酸甲酯（PMMA）基底上的微槽结构起着类似于纸的超亲水膜的作用。我们首先估算了纯水在不同激光能量密度下（9.2 ~ 100.8 J/cm ^2）微槽上的流速。结果表明，通过改变激光辐照参数，可以在0.30 ~ 12.07 μL/s的范围内调节流速。流体流动是可重现的，计算的相对标准偏差（RSD%）小于8%的流速。然后，我们制作了一个用于血液分离的微过滤器，并使用含有树脂微粒的人工血液来评估其过滤能力。该方法在与用于精确试剂操作的纸基诊断装置相关的技术中是有用的。
In this study, we demonstrate the precise control of fluid flow using femtosecond (FS) laser-induced microstructures. A microgroove structure inscribed on a poly(methyl methacrylate) (PMMA) substrate functions as a superhydrophilic membrane similar to paper. We first estimated the flow rate for pure water on microgrooves fabricated at various laser fluences in the range from 9.2 to 100.8 J/cm^2. The results showed that the flow rate could be tuned in the range from 0.30 to 12.07 μL/s by varying the laser irradiation parameters. The fluid flow was reproducible, with a calculated relative standard deviation (RSD%) of less than 8% in the flow rate. We then fabricated a microfilter for blood separation and estimated its filtration ability using artificial blood containing resin microparticles. This method would be useful in a technology related to a paper-based diagnostic device for precise reagent manipulation.