Towards Estimation of Tidal Volume and Respiratory Timings via Wearable-Patch-Based Impedance Pneumography in Ambulatory Settings.
Towards Estimation of Tidal Volume and Respiratory Timings via Wearable-Patch-Based Impedance Pneumography in Ambulatory Settings.
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DOI：
10.1109/tbme.2021.3130540
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发表时间：
2022-06
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在具有新型电极定位的非卧床患者中评价方便的、可穿戴的多频阻抗呼吸描记（IP）呼吸监测。使用可穿戴式多频IP系统估计14名健康受试者的潮气量（TV）和呼吸计时。采用固定在胸骨上的5.1 cm × 5.1 cm四极电极阵列和常规胸部电极配置测量相应的IP信号、贴片和胸部IP。在静态姿势（坐和仰卧）和活动（行走和爬楼梯）期间收集的数据与错误获得的肺量计（SP）容积信号进行了评估。在所有测量中，从补片和胸部IP获得的TV估计值与真实TV的Pearson相关系数（r）分别为0.93±0.05和0.95±0.05，相关均方根误差（RMSE）分别为0.177 L和0.129 L。平均呼吸率（RR）提取30秒段的平均绝对百分比误差（MAPE）为0.93%和0.74%的补丁和胸部IP，分别。同样，确定了贴片和胸部IP的平均吸气和呼气时间，MAPE分别小于6%和4.5%。我们证明了补丁IP执行传统的，繁琐的IP配置。我们还提出了第一次，据我们所知，IP可以鲁棒地估计呼吸的呼吸电视和呼吸时间在american。这项工作代表了通过融合紧凑的胸戴形状因子和多频IP（可随时适应整体心肺监测）实现普遍可穿戴动态呼吸监测的重要一步。
Evaluating convenient, wearable multi-frequency impedance pneumography (IP) based respiratory monitoring in ambulatory persons with novel electrode positioning. A wearable multi-frequency IP system was utilized to estimate tidal volume (TV) and respiratory timings in 14 healthy subjects. A 5.1 cm × 5.1 cm tetrapolar electrode array, affixed to the sternum, and a conventional thoracic electrode configuration were employed to measure the respective IP signals, patch and thoracic IP. Data collected during static postures—sitting and supine—and activities—walking and stair-stepping—were evaluated against a simultaneously-obtained spirometer (SP) volume signal. Across all measurements, estimated TV obtained from the patch and thoracic IP maintained a Pearson correlation coefficient (r) of 0.93±0.05 and 0.95±0.05 to the ground truth TV, respectively, with an associated root-mean-square error (RMSE) of 0.177 L and 0.129 L, respectively. Average respiration rates (RRs) were extracted from 30-second segments with mean-absolute-percentage errors (MAPEs) of 0.93% and 0.74% for patch and thoracic IP, respectively. Likewise, average inspiratory and expiratory timings were identified with MAPEs less than 6% and 4.5% for patch and thoracic IP, respectively. We demonstrated that patch IP performs comparably to traditional, cumbersome IP configurations. We also present for the first time, to the best of our knowledge, that IP can robustly estimate breath-by-breath TV and respiratory timings during ambulation. This work represents a notable step towards pervasive wearable ambulatory respiratory monitoring via the fusion of a compact chest-worn form factor and multi-frequency IP that can be readily adapted for holistic cardiopulmonary monitoring.