The longevity of sirtuins.

The longevity of sirtuins.
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DOI:
10.1016/j.celrep.2012.12.004
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发表时间:
2012-12
期刊:
影响因子:
8.8
通讯作者:
D. Sinclair;E. Verdin
D. Sinclair;E. Verdin
中科院分区:
生物学1区
文献类型:
--
作者:
D. Sinclair;E. Verdin

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Controversy has recently arisen over the role of sirtuins in metazoan aging. In this issue ofCell Reports, Banerjee et al. demonstrate thatDrosophilaSir2 is necessary for life span extension in response to dietary restriction and that its overexpression in the fat body increases the life span.