Separation of hippocampal theta dipoles by partial coherence analysis in the rat.
Separation of hippocampal theta dipoles by partial coherence analysis in the rat.
复制标题
通过部分相干分析分离大鼠海马θ偶极子。
DOI：
10.1016/0006-8993(94)91310-2
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发表时间：
1994
期刊：
影响因子：
2.9
通讯作者：
Vertes,RP
中科院分区：
文献类型：
--
作者：
Kocsis,B;Thinschmidt,JS;Kinney,GG;Vertes,RP
为了分离海马中不同θ发生器的作用并表征它们之间关系的模式，在这项研究中，我们计算了在变化后，记录在（1）CA 1区的层定向物和（2）靠近右侧或左侧海马齿状回中的海马裂的EEG信号之间的相干性，对于第三记录位点也是公共的被消除（偏置）。我们发现，在麻醉和自由活动的大鼠，有一个选择性的高相关性（连贯性）之间的theta节律活动的对侧同侧海马网站。当考虑到对侧海马的任何记录时，同侧浅层和深层记录的场电位之间的一致性被消除。另一方面，对侧同侧θ偶极子之间的一致性并没有减少偏时，由hetero-hetero-hippocampal EEG信号。目前的结果支持了早期关于多个海马theta偶极的发现，并表明可以使用部分相干分析将它们分开。左右浅和深偶极子振荡，好像它们形成了两个独立的系统，一个在两侧的浅CA 1层上延伸，另一个由左右深海马θ偶极子组成。结果还表明，连合投射在大脑半球间θ同步化中起着重要作用。
In order to separate the effect of different theta generators in the hippocampus and to characterize the pattern of relationships between them, in this study, we calculated the coherence that remains between EEG signals, recorded (1) in the stratum oriens of the CA1 region and (2) close to the hippocampal fissure in the dentate gyrus of the right or left hippocampus, after the variations, common also for a third recording site is eliminated (partialization). We found that in both anesthetized and freely moving rats, there is a selective high correlation (coherence) between theta rhythmic activities of contralateral homonymous sites of the hippocampus. The coherence between field potentials recorded in ipsilateral superficial and deep layers was eliminated when allowance was made for any of the contralateral hippocampal recordings. On the other hand, coherence between contralateral homonymous theta dipoles did not decrease when partialized by a heteronymous hippocampal EEG signal. The present results support earlier findings on multiple hippocampal theta dipoles and indicate that they can be separated using partial coherence analysis. The left and right superficial and deep dipoles oscillate as if they formed two separate systems one extending over the superficial CA1 layers on both sides and the other consisting of the left and right deep hippocampal theta dipoles. The results also suggest an important role of the commissural projections in interhemispheric theta synchronization.