Clinical and Radiographic Outcomes of Regenerative Endodontic Procedures in Traumatized Immature Permanent Teeth: Interappointment Dressing or Single-Visit?
Clinical and Radiographic Outcomes of Regenerative Endodontic Procedures in Traumatized Immature Permanent Teeth: Interappointment Dressing or Single-Visit?
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DOI：
10.1016/j.joen.2021.07.013
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发表时间：
2021-09-21
影响因子：
4.2
通讯作者：
de-Jesus-Soares, Adriana
中科院分区：
文献类型：
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作者：
Cerqueira-Neto, Ana Carolina C. L.;Prado, Marina C.;de-Jesus-Soares, Adriana
导言：在确认一次就诊方法对于再生性牙髓治疗(REP)是有效和安全的之前，需要更多的数据。这项研究比较了预约间敷料和单次就诊方案中REPS的临床和放射学结果。方法：将20例年轻牙齿外伤后牙髓坏死患者随机分为2组。在诱导血液凝块之前，牙齿接受6%次氯酸钠和2%洗必泰冲洗，并使用17%EDTA。预约间敷料组(n=11)在支架诱导前用氢氧化钙和2%洗必泰凝胶涂抹21d。单次就诊组(n=9)，支架在一次性就诊时诱导。术后随访24个月。初级、二级和三级结果由3名独立评估者评估。术前和术后拍片定量测量根尖直径、根管宽度、根管长度和颈椎屏障的位置，并用t检验或Mann-Whitney U检验进行组间比较。类别变量采用G检验和Fisher精确检验，连续变量采用Mann-Whitney U检验。统计学意义设为5%。结果：1颗牙齿持续感染。在颈椎屏障的放置方面(P>；0.05)，在初级、二级和三级预后方面(P>；0.05)，以及在定量放射学结果参数(P>；0.05)方面，没有观察到差异。结论：使用预约间敷料或一次就诊方案完成REPS的临床和放射学结果相似。使用6%次氯酸钠、2%洗必泰和17%EDTA的REPS一次访问方案允许在坏死性未成熟恒牙中获得满意的结果。(J Endod 2021；47：1598-1608。)
Introduction: More data are needed before affirming that single-visit approaches are effective and safe for regenerative endodontic procedures (REPs). This study compared clinical and radiographic outcomes of REPs between interappointment dressing or single-visit protocols. Methods: Twenty young patients presenting traumatized immature teeth with pulp necrosis were divided into 2 groups. Teeth were submitted to 6% sodium hypochlorite and 2% chlorhexidine irrigation and to 17% EDTA use before blood clot induction. In the interappointment dressing group (n = 11), calcium hydroxide was used with 2% chlorhexidine gel for 21 days before scaffold induction. In the single-visit group (n = 9), the scaffold was induced during the only appointment. Patients were followed up for 24 months. Primary, secondary, and tertiary outcomes were assessed by 3 independent evaluators. Preoperative and follow-up radiographs were assessed for quantitative measurements of the apical diameter, root width, root length, and cervical barrier placement and compared between groups using the t test or Mann-Whitney U test. Categoric variables were assessed with the G test and the Fisher exact test and continuous variables with the Mann-Whitney U test. Statistical significance was set at 5%. Results: One tooth showed persistence of infection. No difference was observed in cervical barrier placement (P > .05); between groups regarding primary, secondary, and tertiary outcomes (P > .05); and in parameters of quantitative radiographic outcomes (P > .05). Conclusions: Completing REPs with an interappointment dressing or a single-visit protocol presented similar clinical and radiographic outcomes. A single-visit protocol of REPs using 6% sodium hypochlorite, 2% chlorhexidine, and 17% EDTA permitted satisfactory outcomes in necrotic immature permanent teeth. (J Endod 2021;47:1598-1608.)