Intracortical Inhibition Increases during Postural Task Execution in Response to Balance Training
Intracortical Inhibition Increases during Postural Task Execution in Response to Balance Training
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DOI：
10.1016/j.neuroscience.2019.01.007
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发表时间：
2019-03-01
期刊：
影响因子：
3.3
通讯作者：
Taube, W.
中科院分区：
文献类型：
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作者：
Mouthon, A.;Taube, W.
皮质内抑制调制似乎是一个完整的运动控制和运动学习的关键。然而，长期训练对短间隔皮层内抑制（SICI）的影响却鲜有研究。关于平衡，以前的研究表明，随着姿势任务难度的增加，SICI降低，但平衡训练（BT）的效果尚不清楚。本研究测试了BT引起的姿势控制改善是否伴随着SICI的变化。通过在不稳定平台上训练2周的BT组（n = 13）和对照（CON）组（n = 13）中对运动皮层施加成对脉冲磁刺激来测量胫骨前肌中的SICI，同时执行三个渐进性要求的姿势任务：稳定站姿（“稳定”），站在用弹性带（“带”）部分固定的可移动平台上或自由移动（“自由”）。BT组对姿势控制的改善显著高于CON组（“自由”条件：+80% vs. + 21%; p < 0.001）。对于SICI，当任务难度增加时，姿势任务的主效应（F-2，（48）= 24.6; p < 0.001）降低了SICI，并且训练后BT组在所有三个姿势任务中的SICI显著增强导致了时间x组相互作用（F-1，（24）= 5.9; p = 0.02）。SICI的增加与平衡性能的改善显著相关（r = 0.56; p = 0.047）。本研究证实了先前的研究结果的任务特定的调制SICI时，平衡。更重要的是，训练增加了SICI，这种增加与平衡性能的变化相关。因此，SICI的变化似乎不仅涉及控制，而且还涉及在训练中适应直立姿势。(C)2019作者（S）由Elsevier Ltd代表IBRO出版。
Intracortical inhibitory modulation seems crucial for an intact motor control and motor learning. However, the influence of long(er) term training on short-interval intracortical inhibition (SICI) is scarcely investigated. With respect to balance, it was previously shown that with increasing postural task difficulty, SICI decreased but the effect of balance training (BT) is unknown. The present study tested whether improvements in postural control due to BT are accompanied by changes in SICI. SICI was measured in the tibialis anterior by applying paired-pulse magnetic stimuli to the motor cortex in a BT group (n = 13) training 2 weeks on an unstable platform and a control (CON) group (n = 13) while performing three progressively demanding postural tasks: stable stance ('Stable'), standing on a movable platform partly secured with elastic straps ('Straps') or freely moving ('Free'). The BT group improved postural control significantly more than the CON-group ('Free' condition: +80% vs. + 21%; p < 0.001). For SICI, there was a main effect of POSTURAL TASK (F-2, (48) = 24.6; p < 0.001) with decreasing SICI when task difficulty increased and a TIME x GROUP interaction (F-1, (24) = 5.9; p = 0.02) caused by significantly enhanced SICI in the BT group in all three postural tasks after the training. The increases in SICI were significantly correlated with improvements in balance performance (r = 0.56; p = 0.047). The present study confirms previous findings of task-specific modulation of SICI when balancing. More importantly, training was shown to increase SICI and this increase was correlated with changes in balance performance. Thus, changes in SICI seem to be involved not only for the control but also when adapting upright posture with training. (C) 2019 The Author(s). Published by Elsevier Ltd on behalf of IBRO.