Estimated incidence and risk factors of sudden unexpected death
Estimated incidence and risk factors of sudden unexpected death
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DOI：
10.1136/openhrt-2015-000321
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发表时间：
2016-05-01
期刊：
影响因子：
2.7
通讯作者：
Simpson, Ross J., Jr.
中科院分区：
文献类型：
--
作者：
Lewis, Mary Elizabeth;Lin, Feng-Chang;Simpson, Ross J., Jr.
目的：在本文中，我们估计了北卡罗来纳州一个县社会经济和种族多元化人群中猝死的发生率并确定了猝死的风险因素。对猝死的发生率和危险因素的估计差异很大。在北卡罗来纳州的突然意外死亡（SUDDEN）项目是一个基于人口的调查的发病率和潜在的原因，猝死方法：从2013年3月3日至2014年3月2日，所有的院外死亡在威克县，北卡罗来纳州，筛选，以确定推定的突然意外死亡之间的自由生活的居民年龄在18岁至64岁。结果：经鉴定，190例突发性非预期死亡，其中男性122例，女性68例。总体估计发病率为32.1/100 000人-年：男性42.7，女性22.4。大多数受害者是55岁以上的白色未婚男性，在家中无人目睹的死亡。高血压和血脂异常在男性和女性中很常见。非裔美国妇女死于突然意外死亡的比例过高。年龄在55岁以下的女性冠心病占一半以上的女性参与者与coronary artery diseases.Conclusions：突然意外死亡的总体估计发病率可能占约10%的所有死亡分类为“自然”。妇女意外猝死的估计发生率低于男子。然而，我们发现男性和女性之间在年龄或合并症方面没有重大差异。患有冠心病的非洲裔美国人和年轻女性有突然意外死亡的风险。
Objective: In this manuscript, we estimate the incidence and identify risk factors for sudden unexpected death in a socioeconomically and racially diverse population in one county in North Carolina. Estimates of the incidence and risk factors contributing to sudden death vary widely. The Sudden Unexpected Death in North Carolina (SUDDEN) project is a population-based investigation of the incidence and potential causes of sudden death.Methods: From 3 March 2013 to 2 March 2014, all out-of-hospital deaths in Wake County, North Carolina, were screened to identify presumed sudden unexpected death among free-living residents between the ages of 18 and 64 years. Death certificate, public and medical records were reviewed and adjudicated to confirm sudden unexpected death cases.Results: Following adjudication, 190 sudden unexpected deaths including 122 men and 68 women were identified. Estimated incidence was 32.1 per 100 000 person-years overall: 42.7 among men and 22.4 among women. The majority of victims were white, unmarried men over age 55 years, with unwitnessed deaths at home. Hypertension and dyslipidaemia were common in men and women. African-American women dying from sudden unexpected death were over-represented. Women who were under age 55 years with coronary disease accounted for over half of female participants with coronary artery disease.Conclusions: The overall estimated incidence of sudden unexpected death may account for approximately 10% of all deaths classified as 'natural'. Women have a lower estimated incidence of sudden unexpected death than men. However, we found no major differences in age or comorbidities between men and women. African-Americans and young women with coronary disease are at risk for sudden unexpected death.