Trazodone in the treatment of panic disorder and agoraphobia with panic attacks.
Trazodone in the treatment of panic disorder and agoraphobia with panic attacks.
复制标题
曲唑酮治疗惊恐障碍和伴有惊恐发作的广场恐惧症。
DOI：
10.1176/ajp.144.6.785
复制
发表时间：
1987
期刊：
影响因子：
--
通讯作者：
Dealy,R
中科院分区：
文献类型：
--
作者：
Mavissakalian,M;Perel,J;Bowler,K;Dealy,R
Eleven patients with panic disorder or agoraphobia with panic attacks completed an 8-week single-blind trial of trazodone (300 mg/day) without concurrent behavioral instructions. The measures of change included ratings of generalized and panic anxiety, phobias, and depression and a behavioral avoidance test, which were administered during a baseline period of placebo administration and at 4 and 8 weeks of the trial. There was significant improvement on all symptom dimensions, which suggests that trazodone may have specific antipanic and antiphobic actions and underscores the importance of serotonergic mechanisms in these anxiety disorders.
