Functional implication of autophagy in steroid‐secreting cells of the rat
Functional implication of autophagy in steroid‐secreting cells of the rat
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DOI：
10.1002/ar.1092420202
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发表时间：
1995-06
期刊：
影响因子：
--
通讯作者：
J. Yi;Xue-ming Tang
中科院分区：
文献类型：
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作者：
J. Yi;Xue-ming Tang
背景：自噬，虽然经常在胚胎细胞和病理改变细胞中观察到，但在正常的，完全分化的细胞中却很少发生。我们之前的研究表明，大鼠睾丸间质细胞的自噬活性频率相当高，但间质细胞自噬的功能意义尚不清楚。本研究的目的是探讨自噬在类固醇分泌细胞中的可能作用。
Background: Autophagy, while frequently observed in embryonic cells undergoing differentiation and in pathologically altered cells, appears to occur less commonly in normal, fully differentiated cells. Our previous work revealed that the frequency of autophagic activity was rather high in the Leydig cells of rat testes, but the functional significance of autophagy in Leydig cells remains obscure. The purpose of the present study is to investigate the possible role of autophagy in steroid‐secreting cells.