Association of depressive symptoms with functional outcome after traumatic brain injury.
Association of depressive symptoms with functional outcome after traumatic brain injury.
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抑郁症状与创伤性脑损伤后功能结果的关联。
DOI：
10.1097/htr.0b013e3182114efd
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发表时间：
2012
期刊：
影响因子：
--
通讯作者：
Diaz-Arrastia,R
中科院分区：
文献类型：
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作者：
Hudak,AM;Hynan,LS;Harper,CR;Diaz-Arrastia,R
目的：探讨创伤性脑损伤(TBI)后功能状态的改善与抑郁症状的相关性。参与者：共有471名脑外伤患者(72%为白人；71%为男性；格拉斯哥昏迷评分(GCS)中位数为11)在急性护理或住院康复期间登记，并平均随访6个月。主要测量：贝克抑郁量表II(BDI-II)、格拉斯哥预后量表扩展版和功能状态检查(FSE)。结果：我们发现BDI-II评分与FSE总分以及FSE的所有领域之间存在显著的Spearman等级顺序相关。较低的功能水平与更多的抑郁症状相关。对包括受试者特征、损伤相关特征和结果测量在内的预测因素进行建模，得到两个模型，包括年龄和GCS以及其他因素。结论：抑郁症状和功能结果之间的关系是复杂的，值得进一步研究。作者将鼓励临床医生监测患者的抑郁症状，以帮助防止对康复的不利影响。
Objective:To test whether improved functional status correlates with more depressive symptoms after traumatic brain injury (TBI). This is based on the concept that increasing awareness of deficits may exacerbate depression, even while survivors are making functional improvements.Participants:A total of 471 individuals with TBI (72% white; 71% men; median Glasgow Coma Scale (GCS) score= 11) enrolled during acute care or inpatient rehabilitation and followed up at a median of 6 months.Main Measure:Beck Depression Inventory-II (BDI-II), Glasgow Outcome Scale-Extended, and Functional Status Examination (FSE).Results:We found significant Spearman rank order correlations between BDI-II scores and the total FSE as well as all domains of the FSE. Lower functional levels correlated with more depressive symptoms. Modeling of predictive factors, including subject characteristics, injury-related characteristics, and outcome measures, resulted in 2 models, both containing age and GCS along with other factors.Conclusion:The relation between depressive symptoms and functional outcomes is complex and a fertile area for further research. The authors would encourage clinicians to monitor patients for depressive symptoms to help to prevent the detrimental impact on recovery.