Single cell genome sequencing.
Single cell genome sequencing.
复制标题
单细胞基因组测序。
DOI:
10.1016/j.copbio.2011.11.018
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发表时间:
2012-06
影响因子:
7.7
通讯作者:
Singh, Anup K.
中科院分区:
文献类型:
--
作者:
Yilmaz, Suzan;Singh, Anup K.
Whole genome amplification and next-generation sequencing of single cells has become a powerful approach for studying uncultivated microorganisms that represent 90–99 % of all environmental microbes. Single cell sequencing enables not only the identification of microbes but also linking of functions to species, a feat not achievable by metagenomic techniques. Moreover, it allows the analysis of low abundance species that may be missed in community-based analyses. It has also proved very useful in complementing metagenomics in the assembly and binning of single genomes. With the advent of drastically cheaper and higher throughput sequencing technologies, it is expected that single cell sequencing will become a standard tool in studying the genome and transcriptome of microbial communities.
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影响因子:
14.9
作者:
Jensen LJ;Kuhn M;Stark M;Chaffron S;Creevey C;Muller J;Doerks T;Julien P;Roth A;Simonovic M;Bork P;von Mering C
通讯作者:
von Mering C
影响因子:
3.7
作者:
Blainey PC;Mosier AC;Potanina A;Francis CA;Quake SR
通讯作者:
Quake SR
影响因子:
4.5
作者:
Marcy, Yann;Ishoey, Thomas;Lasken, Roger S.;Stockwell, Timothy B.;Walenz, Brian P.;Halpern, Aaron L.;Beeson, Karen Y.;Goldberg, Susanne M. D.;Quake, Stephen R.
通讯作者:
Quake, Stephen R.
影响因子:
3.7
作者:
Fleming EJ;Langdon AE;Martinez-Garcia M;Stepanauskas R;Poulton NJ;Masland ED;Emerson D
通讯作者:
Emerson D
影响因子:
6.1
作者:
Liu P;Meagher RJ;Light YK;Yilmaz S;Chakraborty R;Arkin AP;Hazen TC;Singh AK
通讯作者:
Singh AK