Effective long-range attraction between protein molecules in solutions studied by small angle neutron scattering.
Effective long-range attraction between protein molecules in solutions studied by small angle neutron scattering.
复制标题
通过小角中子散射研究溶液中蛋白质分子之间的有效长程吸引力。
DOI：
10.1103/physrevlett.95.118102
复制
发表时间：
2005
影响因子：
8.6
通讯作者：
Sow
中科院分区：
文献类型：
--
作者：
Yun Liu;E. Fratini;P. Baglioni;Wei;Sow
从细胞色素C和溶菌酶蛋白质溶液的小角中子散射强度分布示出了在一个非常小的波矢量Q，这可以解释在蛋白质分子之间的弱的长程吸引力的存在下的强度上升。这种相互作用的范围是蛋白质分子直径的几倍，远大于屏蔽静电排斥的范围。我们表明，这种长程吸引力是密切相关的阴离子存在的类型和溶液中的离子浓度。
Small angle neutron scattering intensity distributions taken from cytochrome C and lysozyme protein solutions show a rising intensity at a very small wave vector Q, which can be interpreted in terms of the presence of a weak long-range attraction between protein molecules. This interaction has a range several times that of the diameter of the protein molecule, much greater than the range of the screened electrostatic repulsion. We show evidence that this long-range attraction is closely related to the type of anion present and ion concentration in the solution.