The emergence of group B streptococci in infections of the newborn infant.
The emergence of group B streptococci in infections of the newborn infant.
复制标题
B 族链球菌在新生儿感染中的出现。
作者：
B. Anthony;D. Okada
由于长期与奶牛乳腺炎相关，B组链球菌（无乳链球菌）是一种具有相当兽医和经济重要性的病原体（1）。然而，它只是在过去15年内才取得了医学上的突出地位。自1962年以来，已报告了500多例新生儿B族链球菌败血症2，并描述了许多其他病例，但记录不太严格。在美国，这种微生物现在是新生儿严重细菌感染的主要原因（2-5），或至少与大肠杆菌（2）共享这种区别。在美国和英国的几个中心，B组链球菌败血症的发病率估计为每1000例活产1.3 - 3例（2，6-9）。本章强调新生儿链球菌感染的临床和相关的微生物学和流行病学方面。Eickhoff在1972年综述了与B族链球菌相关的人类疾病的更一般性主题（10）。
Because of a long association with mastitis in dairy cattle, the group B streptococcus (Streptococcus agalactiae) is an agent of considerable veterinary and economic importance (1). However, it has achieved medical prominence only within the past 15 years. Since 1962, well over 500 instances of group B streptococcal sepsis2 in newborn infants have been reported and many other cases, less stringently docu mented, have been described. In the United States, this organism is now the leading cause of serious bacterial infections in newborns (2-5) or at least shares this distinc tion with Escherichia coli (2). The incidence of group B streptococcal sepsis in several American and British centers has been estimated at between 1.3 and 3 per 1, 000 live births (2, 6-9). This chapter emphasizes clinical and relevant microbiological and epidemiologi cal aspects of newborn streptococcal infections. The more general subject of human disease related to group B streptococci was reviewed by Eickhoff in 1972 (10).