Positron emission tomographic studies during serial word-reading by normal and dyslexic adults.
Positron emission tomographic studies during serial word-reading by normal and dyslexic adults.
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正常和诵读困难成年人连续单词阅读过程中的正电子发射断层扫描研究。
DOI：
10.1080/01688639108401069
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发表时间：
1991
影响因子：
2.2
通讯作者：
Sevush,S
中科院分区：
文献类型：
--
作者：
Gross-Glenn,K;Duara,R;Barker,WW;Loewenstein,D;Chang,JY;Yoshii,F;Apicella,AM;Pascal,S;Boothe,T;Sevush,S
正电子发射断层扫描（PET）被用来研究区域的大脑代谢活动，在口头阅读在右利手的成年男性，并没有儿童和家族史的发展性阅读障碍。显着的组间差异，正常化的区域代谢值显示在前额叶皮层和枕叶的舌（下）区域。与正常阅读者相比，阅读障碍者的双侧舌侧值更高。在阅读过程中，非阅读障碍者的前额叶和舌区的不对称性与此相反，阅读障碍者的模式更为对称。这些结果表明，与没有这种童年史的人相比，儿童时期患有家族性发展性阅读障碍的人在成年后的阅读过程中激活了不同的大脑区域。
Positron-emission tomography (PET) was used to study regional cerebral metabolic activity during oral reading in right-handed adult males with, and without a childhood and family history of developmental dyslexia. Significant group differences in normalized regional metabolic values were revealed in prefrontal cortex and in the lingual (inferior) region of the occipital lobe. Lingual values were bilaterally higher for dyslexic than normal readers. In contrast to the asymmetry observed in prefrontal and lingual regions in nondyslexic subjects during reading, the dyslexic pattern was more symmetric. These results demonstrate that individuals who suffered from familial developmental dyslexia as children, activate different brain regions during reading as adults, as compared to individuals without such childhood history.