Gastrointestinal colonization by Candida albicans mutant strains in antibiotic-treated mice.
Gastrointestinal colonization by Candida albicans mutant strains in antibiotic-treated mice.
复制标题
白色念珠菌突变株在抗生素治疗的小鼠中的胃肠道定植。
DOI：
10.1128/cdli.8.1.192-195.2001
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发表时间：
2001
期刊：
影响因子：
--
通讯作者：
Wells,CL
中科院分区：
文献类型：
--
作者：
Wiesner,SM;Jechorek,RP;Garni,RM;Bendel,CM;Wells,CL
经口接种三种白色念珠菌菌株（包括两种突变菌株）之一或土著透明念珠菌的抗生素处理小鼠显示出菌株特异性的念珠菌胃肠道定植水平。然而，无论菌株如何，胃中的活念珠菌数量均为中等至高，小肠上部始终最低，肠道向下逐渐增加。
Antibiotic-treated mice orally inoculated with one of threeCandida albicansstrains (including two mutant strains) or indigenousCandida pelliculosashowed levels of candidal gastrointestinal colonization that were strain specific. However, regardless of strain, the numbers of viable candida were intermediate to high in the stomach, were consistently lowest in the upper small intestine, and increased progressively down the intestinal tract.