Dynamics of virus infections involved in the bovine respiratory disease complex in Swedish dairy herds
Dynamics of virus infections involved in the bovine respiratory disease complex in Swedish dairy herds
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DOI：
10.1016/j.tvjl.2005.04.029
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发表时间：
2006-09-01
影响因子：
2.2
通讯作者：
Alenius, S.
中科院分区：
文献类型：
--
作者：
Hagglund, S.;Svensson, C.;Alenius, S.
对瑞典西南部118个奶牛群的牛呼吸道合胞病毒(BRSV)、牛副流感病毒3(PIV-3)、牛冠状病毒(BCOV)和牛病毒性腹泻病毒(BVDV)的感染动态进行了研究。通过对每群3头至7头与15个月大的小牛的配对样本进行血清学分析，在大约1年的时间里调查了感染的传播情况。结果表明，至少有74%的犊牛在类似7月龄时(样本1，春天)经历过一次或多次监测到的感染，BRSV、PIV-3、BCOV和BVDV的血清阳性分别为30%、48%、34%和8%。BRSV、PIV-3、BCOV和BVDV的血清转阴率分别为26%、38%、50%和3%，63%的动物在类似于15个月的时间内对两种或两种以上的感染有抗体(样本2)。总体而言，在样本1中呈阳性的动物中，90-97%的动物在样本2中保持阳性。BVDV和BCOV之间存在显著的相关性(P=0.01)。此外，与观察到疾病的牛群相比，没有记录有呼吸道疾病病史的牛群(n=15)在所有四种感染中被归类为阴性的比例明显更高(P=0.0002)。这项研究表明，在瑞典的一个地区，幼年动物的感染负担很高，BRSV、PIV-3和BCOV有效传播。BVDV感染仅限于几个牛群，这反映了瑞典针对BVDV的自愿控制计划的效果。(C)2005爱思唯尔有限公司。保留所有权利。
The dynamics of bovine respiratory syncytial virus (BRSV), bovine parainfluenza virus 3 (PIV-3), bovine corona virus (BCoV) and bovine viral diarrhoea virus (BVDV) infections were studied in 118 dairy herds in south western Sweden. By using serology on paired samples from three similar to 7 vs. similar to 15-month-old calves per herd, the propagation of infections was investigated over about a 1-year period. The results implied that at least 74% of calves had experienced one or more of the monitored infections at the age of similar to 7 months (Sample 1, Spring); 30%, 48%, 34% and 8% were seropositive to BRSV, PIV-3, BCoV and BVDV, respectively. Seroconversions to BRSV, PIV-3, BCoV and BVDV occurred in 26%, 38%, 50% and 3% of seronegative animals and 63% had antibodies against two or more infections at similar to 15 months (Sample 2). In total, 90-97% of animals that were seropositive in Sample 1 remained positive in Sample 2. A significant association was found between BVDV and BCoV (P = 0.01). Moreover, a significantly higher proportion of herds in which no calves had a recorded history of respiratory disease (n = 15) were classified as negative to all four infections monitored when compared to herds in which disease was observed (P = 0.0002). This study showed a high infection burden in young animals and effective spread of BRSV, PIV-3 and BCoV in one area of Sweden. BVDV infections were restricted to a few herds, reflecting the effect of a voluntary control program against BVDV in Sweden. (c) 2005 Elsevier Ltd. All rights reserved.