Microbe Profile: Pseudomonas aeruginosa: opportunistic pathogen and lab rat
Microbe Profile: Pseudomonas aeruginosa: opportunistic pathogen and lab rat
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DOI：
10.1099/mic.0.000860
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发表时间：
2020-01-01
期刊：
影响因子：
2.8
通讯作者：
Whiteley, Marvin
中科院分区：
文献类型：
--
作者：
Diggle, Stephen P.;Whiteley, Marvin
铜绿假单胞菌是一种革兰氏阴性条件致病菌，是研究细菌毒力和社会性的模式菌。虽然它可以从包括土壤和水在内的各种环境中分离出少量，但它几乎可以在任何人类/动物影响的环境中找到。它是具有免疫抑制和慢性病症的人类的疾病和死亡的主要原因，并且由于许多抗生素耐药性机制和生物体形成多细胞生物膜的倾向，这些患者的感染难以治疗。
Pseudomonas aeruginosa is a Gram-negative opportunistic pathogen and a model bacterium for studying virulence and bacterial social traits. While it can be isolated in low numbers from a wide variety of environments including soil and water, it can readily be found in almost any human/animal-impacted environment. It is a major cause of illness and death in humans with immunosuppressive and chronic conditions, and infections in these patients are difficult to treat due to a number of antibiotic resistance mechanisms and the organism's propensity to form multicellular biofilms.