Glistenings in the AcrySof intraocular lens: Pilot study
Glistenings in the AcrySof intraocular lens: Pilot study
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DOI：
10.1016/s0886-3350(00)00700-8
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发表时间：
2001-05-01
影响因子：
2.8
通讯作者：
Christiansen, K
中科院分区：
文献类型：
--
作者：
Christiansen, G;Durcan, FJ;Christiansen, K
目的：评估 AcrySof (R) 人工晶状体 (IOL) 中反光的发生率、严重程度和视觉意义，并确定是否有必要对该晶状体进行大规模深入研究。地点：美国犹他州盐湖城犹他大学 John Moran 眼科中心。方法：连续选择过去 4 年在 1 个机构植入 AcrySof IOL 的患者。对 42 只进行了超声乳化手术并植入 AcrySof IOL 的眼睛进行了评估。检查包括视力、眩光、对比敏感度、散瞳眼底和散瞳裂隙灯评估。在裂隙灯上对 IOL 的反光进行分级，从微量到 4+。结果：所有 42 个 IOL 都有一定程度的晶状体反光。 27 个人工晶状体 (64%) 中的闪光分级为微量，5 个 (12%) 中为 1 +，5 个 (12%) 中为 2+，3 个 (7%) 中为 3+，2 个 (5%) 中为 4+。严重反光（大于或等于 2+）眼睛的斯内伦敏锐度比轻度反光（+）眼睛低二分之一线（P = .01）。在所有眼睛中，亮度敏锐度测试仪得分比斯内伦敏锐度低半行多一点，并且在闪光等级高于 2+ 的眼睛中相差 1 整行。 15 个 IOL 中有 14 个 (93%) 的闪光等级大于痕迹，已在眼睛中使用超过 1 年。没有证据表明反光会影响对比敏感度。结论 AcrySof IOL 经常出现反光，且大多数情况较轻微。需要对这种晶状体进行更大规模的研究，以确定严重的表现是否会影响视觉功能，并了解反光如何随时间变化。
Purpose: To evaluate the prevalence, severity, and visual significance of glistenings seen in the AcrySof (R) intraocular lens (IOL) and determine whether a large in-depth study of this lens is warranted.Setting: John Moran Eye Center, University of Utah, Salt Lake City, Utah, USA.Methods: Patients who had the AcrySof IOL implanted at 1 institution over the past 4 years were serially selected. Forty-two eyes that had phacoemulsification with implantation of the AcrySof IOL were evaluated. The examination consisted of visual acuity, glare, contrast sensitivity, and dilated fundus and dilated slitlamp evaluations. Glistenings in the IOL were graded at the slitlamp from trace to 4+.Results: All 42 IOLs had some degree of lenticular glistenings. The glistenings were graded as trace in 27 IOLs (64%), 1 + in 5 (12%), 2+ in 5 (12%), 3+ in 3 (7%), and 4+ in 2 (5%). The Snellen acuity in eyes with severe glistenings (greater than or equal to2+) was one-half line lower than in eyes with mild glistenings (+) (P = .01). In all eyes, the Brightness Acuity Tester score was a little more than one-half line lower than the Snellen acuity, and the difference was 1 full line in eyes with glistenings graded above 2+. Fourteen of 15 IOLs (93%) with glistenings graded greater than trace had been in the eye for more than 1 year. There was no evidence that contrast sensitivity was affected by the glistenings.Conclusions Glistenings occurred frequently in AcrySof IOLs, with most cases mild. A larger study of this lens is needed to determine whether severe presentations affect visual function and to understand how glistenings change over time.