Model for curvature-driven pearling instability in membranes
Model for curvature-driven pearling instability in membranes
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DOI：
10.1103/physrevlett.99.088101
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发表时间：
2007-08-24
影响因子：
8.6
通讯作者：
Hernandez-Machado, A.
中科院分区：
文献类型：
--
作者：
Campelo, F.;Hernandez-Machado, A.
提出了一种处理膜动态不稳定性的相场模型。我们用它来研究由膜上的两亲性聚合物锚定引起的囊泡中的曲率驱动的珍珠化不稳定性。在这个模型中，我们得到了最近实验中报道的形态变化。形成均匀的珠光体结构是通过随后从顶端对初始圆柱管进行珠光化来实现的。对于足够高的锚浓度，我们从理论上证明了均匀的珍珠状形状在能量上不如非均匀形状的珠状形状，大的球体连接着一系列小的球体。
A phase-field model for dealing with dynamic instabilities in membranes is presented. We use it to study curvature-driven pearling instability in vesicles induced by the anchorage of amphiphilic polymers on the membrane. Within this model, we obtain the morphological changes reported in recent experiments. The formation of a homogeneous pearled structure is achieved by consequent pearling of an initial cylindrical tube from the tip. For high enough concentration of anchors, we show theoretically that the homogeneous pearled shape is energetically less favorable than an inhomogeneous one, with a large sphere connected to an array of smaller spheres.