Postnatal psychiatric morbidity:: a validation study of the GHQ-12 and the EPDS as screening tools

Postnatal psychiatric morbidity:: a validation study of the GHQ-12 and the EPDS as screening tools
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DOI:
10.1016/j.genhosppsych.2006.10.004
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发表时间:
2007-01-01
影响因子:
7
通讯作者:
Martin-Santos, Rocio
Martin-Santos, Rocio
中科院分区:
医学2区
文献类型:
--
作者:
Navarro, Purificacion;Ascaso, Carlos;Martin-Santos, Rocio

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目的:评价12个条目的一般健康问卷(GHQ-12)和爱丁堡产后抑郁量表(EPDS)在筛查最常见的产后精神疾病(情绪、焦虑和适应障碍)方面的有效性。首先,在产后6周访问的1453名妇女完成了GHQ-12和EPDS问卷。其次,根据EPDS的结果,参与者在每一层中被分层并随机选择进行临床评估[DSM-IV结构化临床访谈(SLID)]。采用受试者操作特征(ROC)分析。结果:问卷的同时效度(0.80)令人满意。在最佳分界值下,GHQ-12和EPDS分别产生了非常好的敏感性(80;85.5)和特异性(80.4;85.3)。ROC曲线显示EPDS(AUC=0.933)略优于GHQ-12(AUC=0.904)。结论:GHQ-12和EPDS都是检测产后抑郁、焦虑和适应障碍的有效工具。(C)2007 Elsevier Inc.保留所有权利。
Objective: To assess the validity of the 12-Item General Health Questionnaire (GHQ-12) and the Edinburgh Postnatal Depression Scale (EPDS) in screening for the most common postnatal psychiatric morbidities (mood, anxiety and adjustment disorders).Method: A two-phase cross-sectional study was designed. First, a sample of 1453 women visiting at 6 weeks postpartum completed the GHQ-12 and the EPDS questionnaires. Second, based upon EPDS outcomes, participants were stratified and randomly selected within each stratum for clinical evaluation [Structured Clinical Interview for DSM-IV (SLID)]. Receiver operating characteristic (ROC) analysis was used.Results: The concurrent validity was satisfactory (0.80). At optimum cut-off scores, both GHQ-12 and EPDS yielded very good sensitivity (80; 85.5) and specificity (80.4; 85.3), respectively. ROC curves showed that the performance of the EPDS (AUC=0.933) is slightly superior to that of GHQ-12 (AUC=0.904).Conclusion: Both GHQ-12 and EPDS are valid instruments to detect postnatal depression as well as postnatal anxiety and adjustment disorders. (c) 2007 Elsevier Inc. All rights reserved.