Histopathological changes following removal of the perineurium.
Histopathological changes following removal of the perineurium.
复制标题
去除神经束膜后的组织病理学变化。
DOI：
10.3171/jns.1980.53.2.0233
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发表时间：
1980
影响因子：
4.1
通讯作者：
R. Acland
中科院分区：
文献类型：
--
作者：
J. Nesbitt;R. Acland
使用显微外科技术，将神经束膜鞘从大鼠坐骨神经上剥离超过0.5cm长，在神经由单个神经束组成的点处。于伤后0 ~ 84天切取神经，行半薄横切面检查。一个新的鞘，非常类似于正常的神经束膜，成为组织在第一个10天，它出现均匀的长度损伤段。新的神经束膜鞘可能是由神经内膜成纤维细胞从神经束内迁移形成的。在未受损的标本中，离体神经束膜下方的asons没有发生退行性变化。
Using microsurgical techniques, the perineurial sheath was stripped off the sciatic nerves of rats over a 0.5 cm length at a point where the nerve consists of a single fascicle. The nerves were excised 0 to 84 days after the injury, and were examined in semi-thin transverse section. A new sheath, closely resembling normal perineurium, became organized during the first 10 days; it appeared uniformly over the length of the injured segment. The new perineurial sheath was probably formed by endoneurial fibroblasts migrating from within the fascicle. In undamaged specimens, the asons immediately beneath the excised perineurium underwent no degenerative changes.