Multiphasic MR imaging: a new method for direct imaging of pulsatile CSF flow.
Multiphasic MR imaging: a new method for direct imaging of pulsatile CSF flow.
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多相磁共振成像：脉动脑脊液流直接成像的新方法。
DOI：
10.1148/radiology.161.3.3786732
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发表时间：
1986
期刊：
影响因子：
19.7
通讯作者：
Brady,TJ
中科院分区：
文献类型：
--
作者：
Edelman,RR;Wedeen,VJ;Davis,KR;Widder,D;Hahn,P;Shoukimas,G;Brady,TJ
描述了一种新技术，允许在单次采集中创建纯脉动流磁共振（MR）图像。使用梯度回波脉冲序列获得跨越整个心动周期的5至16幅心电图门控图像。该部分可以从4 mm厚到全厚度投影变化。单独来看，每幅图像都提供了对流动方向和速度的直接评估。图像对的减法消除了从静止质子检测到的信号，产生脉动流的图像。在这项研究中，该技术被用来成像的健康受试者和一名患者的脑脊液（CSF）的流动与脊髓积水。这些数据表明，多相MR成像提供了一个强有力的手段，CSF脉动流动力学的非侵入性评估，并可能有潜在的临床应用调查的各种异常，如正常压力脑积水，空洞，脊髓阻滞。
A new technique is described that allows for the creation of pure pulsatile flow magnetic resonance (MR) images in a single acquisition. Five to 16 electrocardiographically gated images spanning the entire cardiac cycle are obtained with use of a gradient-echo pulse sequence. The section can be varied from 4 mm thick to full thickness projection. Taken singly, each image provides direct assessment of flow direction and velocity. Subtraction of image pairs eliminates signal detected from stationary protons, producing images of pulsatile flow. In this study the technique was used to image the flow of cerebrospinal fluid (CSF) in healthy subjects and in one patient with syringohydromyelia. The data suggest that multiphasic MR imaging provides a powerful means for the noninvasive assessment of CSF pulsatile flow dynamics and may have potential clinical application for the investigation of a variety of abnormalities such as normal pressure hydrocephalus, syrinx, and spinal block.