Herbal medicines for asthma: a systematic review
Herbal medicines for asthma: a systematic review
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DOI：
10.1136/thorax.55.11.925
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发表时间：
2000-11-01
期刊：
影响因子：
10
通讯作者：
Ernst, E
中科院分区：
文献类型：
--
作者：
Huntley, A;Ernst, E
背景-哮喘是现代社会最常见的慢性疾病之一，越来越多的证据表明其发病率和严重程度正在增加。哮喘补充药物的使用率很高。草药制剂被英国哮喘患者列为第三大最受欢迎的补充治疗方式。进行这项研究，以确定是否有任何证据的临床疗效的草药制剂治疗哮喘symptoms.Methods-Four独立的文献检索进行Medline，Pubmed，科克伦图书馆，和Embase。仅纳入随机临床试验。对出版物的语言没有限制。提取的数据在一个标准化的，预定义的方式和评估critically. Results十七随机临床试验中发现，其中6个涉及使用传统的中草药和8个描述传统的印度医学，其中5个调查印度娃儿藤。另外三项随机试验测试了日本汉方药物，大麻和干常春藤叶提取物。17项试验中有9项报告了肺功能和/或症状scores. Conclusions的临床相关改善，没有明确的证据，任何草药制剂出现。考虑到草药在哮喘患者中的普及，迫切需要对草药制剂治疗哮喘进行严格设计的临床相关随机临床试验。
Background-Asthma is one of the most common chronic diseases in modern society and there is increasing evidence to suggest that its incidence and severity are increasing. There is a high prevalence of usage of complementary medicine for asthma. Herbal preparations have been cited as the third most popular complementary treatment modality by British asthma sufferers. This study was undertaken to determine if there is any evidence for the clinical efficacy of herbal preparations for the treatment of asthma symptoms.Methods-Four independent literature searches were performed on Medline, Pubmed, Cochrane Library, and Embase. Only randomised clinical trials were included. There were no restrictions on the language of publication. The data were extracted in a standardised, predefined manner and assessed critically.Results-Seventeen randomised clinical trials were found, six of which concerned the use of traditional Chinese herbal medicine and eight described traditional Indian medicine, of which five investigated Tylophora indica. Three other randomised trials tested a Japanese Kampo medicine, marihuana, and dried ivy leaf extract. Nine of the 17 trials reported a clinically relevant improvement in lung function and/or symptom scores.Conclusions-No definitive evidence for any of the herbal preparations emerged. Considering the popularity of herbal medicine with asthma patients, there is urgent need for stringently designed clinically relevant randomised clinical trials for herbal preparations in the treatment of asthma.