Diagnostic accuracy of Noninvasive tests to evaluate bladder outlet obstruction in men:: Detrusor wall thickness, uroflowmetry, postvoid residual urine, and prostate volume
Diagnostic accuracy of Noninvasive tests to evaluate bladder outlet obstruction in men:: Detrusor wall thickness, uroflowmetry, postvoid residual urine, and prostate volume
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DOI：
10.1016/j.eururo.2006.12.023
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发表时间：
2007-09-01
期刊：
影响因子：
23.4
通讯作者：
Wijkstra, Hessel
中科院分区：
文献类型：
--
作者：
Oelke, Matthias;Hoefner, Klaus;Wijkstra, Hessel
目的：本前瞻性研究的目的是比较逼尿肌壁厚度（DWT）、游离尿流率、排尿后残余尿和前列腺体积的诊断准确性（指数测试），带压力-流量研究方法：在2年期间，年龄大于40岁的具有下尿路症状和/或前列腺增大的男性进行以下测试：超声测量DWT、自由尿流率（Q（max）、Q（ave））、排尿后残余尿和前列腺体积。压力-流量研究被用来划分阻塞从nonobstructed bladders.Results：160名男性之间的40-89岁（中位数：62岁）被列入研究; 75例（46.9%）BOO根据压力-流量研究。所有调查的指数测试的结果有显着差异阻塞和nonobstructive男子。DWT是确定BOO的最准确的测试：阳性预测值为94%，特异性为95%，ROC分析曲线下面积为0.93。DWT测量结果与压力-流量study.Conclusions的结果之间的一致性为89%：DWT测量可以检测BOO比自由尿流率，排尿后残余尿，或前列腺体积。在临床常规中，DWT测量可用于无创地判断BOO。(c)2007年欧洲泌尿外科协会。Elsevier B. V.出版，保留所有权利。
Objectives: The aim of this prospective study was to compare the diagnostic accuracy of detrusor wall thickness (DWT), free uroflowmetry, postvoid residual urine, and prostate volume (index tests) with pressure-flow studies (reference standard) to detect bladder outlet obstruction (BOO) in men.Methods: During a 2-yr period, men older than 40 yr with lower urinary tract symptoms and/or prostatic enlargement had the following tests: ultrasound measurements of DWT, free uroflowmetry (Q(max), Q(ave)), Postvoid residual urine, and prostate volume. Pressure-flow studies were used to divide obstructed from nonobstructed bladders.Results: One hundred sixty men between 40-89 yr of age (median: 62 yr) were included in the study; 75 patients (46.9%) had BOO according to pressure-flow studies. The results of all investigated index tests differed significantly between obstructed and nonobstructed men. DWT was the most accurate test to determine BOO: the positive predictive value was 94%, specificity 95%, and the area under the curve of ROC analysis 0.93. There was an agreement of 89% between the results of DWT measurement and pressure-flow studies.Conclusions: Measurements of DWT can detect BOO better than free uroflowmetry, postvoid residual urine, or prostate volume. In clinical routine, DWT measurements can be used to judge BOO noninvasively. (c) 2007 European Association of Urology. Published by Elsevier B.V. All rights reserved.