Tau reduction prevents A-induced axonal transport deficits by blocking activation of GSK 3
Tau reduction prevents A-induced axonal transport deficits by blocking activation of GSK 3
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发表时间：
2015
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通讯作者：
K. Vossel;Jordan C. Xu;V. Fomenko;T. Miyamoto;Elsa Suberbielle;Joseph A. Knox;Kaitlyn Ho;Daniel H. Kim;Gui-qiu Yu;L. Mucke
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作者：
K. Vossel;Jordan C. Xu;V. Fomenko;T. Miyamoto;Elsa Suberbielle;Joseph A. Knox;Kaitlyn Ho;Daniel H. Kim;Gui-qiu Yu;L. Mucke
洛克菲勒大学出版社$30.00细胞生物学杂志第209卷第3期419-433 www.jcb.org/cgi/doi/10.1083/jcb.201407065 JCB 419致基思A.本文kvossel@gladstone.ucsf.edulmucke@gladstone.ucsf.edu中使用的缩写：A β，淀粉样蛋白β; AD，阿尔茨海默病; ANOVA，方差分析; [Ca]i，细胞内钙; D-AP 5，d-（N）-2氨基-5-膦酰基戊酸; DIV，体外天数; DPBS，Dulbecco磷酸盐缓冲盐水; GSK 3 β，糖原合成酶激酶3 β; GSM，β-分泌酶调节剂; hAPP，人淀粉样蛋白前体蛋白; NMDAR，N-甲基-d-天冬氨酸受体; PS1，早老素1; TTX，河豚毒素。介绍
The Rockefeller University Press $30.00 J. Cell Biol. Vol. 209 No. 3 419–433 www.jcb.org/cgi/doi/10.1083/jcb.201407065 JCB 419 Correspondence to Keith A. Vossel: kvossel@gladstone.ucsf.edu; or Lennart Mucke: lmucke@gladstone.ucsf.edu Abbreviations used in this paper: A, amyloid ; AD, Alzheimer’s disease; ANOVA, analysis of variance; [Ca]i, intracellular calcium; D-AP5, d-()-2amino-5-phosphonopentanoic acid; DIV, day in vitro; DPBS, Dulbecco’s phosphatebuffered saline; GSK3, glycogen synthase kinase 3; GSM, -secretase modulator; hAPP, human amyloid precursor protein; NMDAR, N-methyl-d-aspartate receptor; PS1, presenilin 1; TTX, tetrodotoxin. Introduction