ANOGENITAL RATIO - MEASURE OF FETAL VIRILIZATION IN PREMATURE AND FULL-TERM NEWBORN-INFANTS
ANOGENITAL RATIO - MEASURE OF FETAL VIRILIZATION IN PREMATURE AND FULL-TERM NEWBORN-INFANTS
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DOI：
10.1016/s0022-3476(87)80075-6
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发表时间：
1987-08-01
影响因子：
5.1
通讯作者：
BRASEL, JA
中科院分区：
文献类型：
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作者：
CALLEGARI, C;EVERETT, S;BRASEL, JA
为了提供标准化的数据，我们测量了115名胎龄在25-42周的婴儿和10名孕妇的肛门生殖距离，包括肛门到阴蒂底部(AF)、肛门到阴蒂底部(AC)和四针到阴蒂底部(FC)。所有婴儿的测量结果都与体表面积、体重、身长和胎龄呈显著正相关(P<；0.001)。然而，肛门生殖比率(AF/AC)服从正态分布，与任何人体测量学变量或年龄无关。婴儿的平均(±-.SD)值为0.37±-。0.07，成人为0.36。+-。0.07。肛门生殖器比率>；0.50低于95%的可信区间，提示阴唇融合，需要进一步评估。因为它与身体大小和胎龄无关，所以肛门生殖器比率在诊断雄激素诱导的早产儿和足月女婴的唇阴囊融合中应该是有用的。
To provide normative data, we measured anogenital distances in 115 infants of 25 to 42 weeks gestational age and 10 pregnant women, including anus to fourchette (AF), anus to base of the clitoris (AC), and fourchette to base of the clitoris (FC). All infant measurements showed positive and significant correlations with body surface area, weight, length, and gestational age (P < 0.001). However, the anogenital ratio (AF/AC) followed a normal distribution and did not correlate with any of the anthropometric variables or age. Mean (.+-.SD) value in infants was 0.37 .+-. 0.07, and in adults, 0.36 .+-. 0.07. An anogenital ratio > 0.50 falls outside the 95% confidence limits, suggests labioscrotal fusion, and indicates a need for further evaluation. Because it is independent of body size and gestational age, the anogenital ratio should be useful in diagnosing androgen-induced labioscrotal fusion in both premature and full-term female infants.