The effect of notification window length on the epidemiological impact of COVID-19 contact tracing mobile applications.
The effect of notification window length on the epidemiological impact of COVID-19 contact tracing mobile applications.
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DOI：
10.1038/s43856-022-00143-2
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发表时间：
2022
期刊：
影响因子：
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通讯作者：
Thompson, Robin N
中科院分区：
文献类型：
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作者：
Leng, Trystan;Hill, Edward M;Keeling, Matt J;Tildesley, Michael J;Thompson, Robin N
移动的接触者追踪应用程序（应用程序）促进的SARS-CoV-2传播的减少取决于通知的相关接触者的比例以及这些接触者在通知后被隔离的概率。通知的相关联系人的比例取决于感染者检测呈阳性之前通知其联系人的天数，我们将其称为应用程序的通知窗口。我们使用SARS-CoV-2传播的流行病学模型，该模型捕获了感染的概况，以考虑通知窗口长度和主动应用程序使用之间的权衡。我们专注于5天及2天窗口，即英格兰及威尔士的NHS COVID-19应用程序于二零二一年八月二日之前及之后的通知窗口。我们的分析表明，在相同的活跃应用程序使用水平下，5天的窗口比2天的窗口导致更大的传输减少。但是，如果短通知窗口与更高级别的活跃应用程序使用和在通知时遵守隔离相关联，则短通知窗口在减少传输方面可能更有效。我们的研究结果表明，在为COVID-19接触者追踪应用程序设置通知窗口时，了解遵守干预措施的重要性。Leng等人通过数学建模研究了通知窗口长度对COVID-19接触者追踪移动的应用程序流行病学影响的影响。他们证明，如果短窗口与更高水平的活跃应用程序使用和在通知时遵守隔离相关联，则短窗口在减少传播方面可以更有效。
The reduction in SARS-CoV-2 transmission facilitated by mobile contact tracing applications (apps) depends both on the proportion of relevant contacts notified and on the probability that those contacts quarantine after notification. The proportion of relevant contacts notified depends upon the number of days preceding an infector’s positive test that their contacts are notified, which we refer to as an app’s notification window. We use an epidemiological model of SARS-CoV-2 transmission that captures the profile of infection to consider the trade-off between notification window length and active app use. We focus on 5-day and 2-day windows, the notification windows of the NHS COVID-19 app in England and Wales before and after 2nd August 2021, respectively. Our analyses show that at the same level of active app use, 5-day windows result in larger reductions in transmission than 2-day windows. However, short notification windows can be more effective at reducing transmission if they are associated with higher levels of active app use and adherence to isolation upon notification. Our results demonstrate the importance of understanding adherence to interventions when setting notification windows for COVID-19 contact tracing apps. Leng et al. study the effect of notification window length on the epidemiological impact of COVID-19 contact tracing mobile apps with mathematical modelling. They demonstrate that short windows can be more effective at reducing transmission if they are associated with higher levels of active app usage and adherence to isolation upon notification.