Penile erection produced by microstimulation of the sacral spinal cord of the cat.
Penile erection produced by microstimulation of the sacral spinal cord of the cat.
复制标题
通过微刺激猫的骶脊髓而产生阴茎勃起。
DOI：
10.1109/86.736151
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发表时间：
1998
期刊：
影响因子：
--
通讯作者：
Roppolo,JR
中科院分区：
文献类型：
--
作者：
Tai,C;Booth,AM;deGroat,WC;Roppolo,JR
通过测量刺激骶神经前根和骶脊髓引起的海绵窦压力（CSP）的变化，研究了猫骶神经介导阴茎勃起的神经通路。刺激脊神经根后，S1节段诱发的CSP反应最大，而S2和S3节段最小。在S1脊髓微刺激引起大CSP反应，但小或没有膀胱收缩。最大的CSP反应诱发的中间的S1腹角，脊髓表面下1.6-2.8毫米和中线和灰质的侧边缘之间的中间微刺激。该区域为200-400 μ m宽（内侧至外侧），并在吻尾方向上延伸1-2 mm。脊髓微刺激的最大CSP反应是由50-150 /spl mu/A的刺激强度，0.2 ms的脉冲宽度和30-40 Hz的频率引起的，并在延迟8-40 s后发生。这项研究表明，骶脊髓的局灶性微刺激可能有助于引起脊髓损伤患者的阴茎勃起活动。
The sacral neural pathways mediating penile erection in the cat were studied by measuring the change in cavernous sinus pressure (CSP) elicited by stimulation of the sacral ventral roots or by microstimulation of the sacral spinal cord. Ventral root stimulation revealed that the S1 segment rather than S2 and S3 spinal segments could evoke the largest CSP responses. Microstimulation in the S1 spinal cord elicited large CSP responses but small or no bladder contractions. Maximal CSP responses were evoked by microstimulation in the middle of the S1 ventral horn, 1.6-2.8 mm below the cord surface and midway between the midline and the lateral edge of the gray matter. The area was 200-400 pm wide (medial to lateral) and extended 1-2 mm in the rostrocaudal direction. Maximal CSP responses to spinal cord microstimulation were elicited by stimulus intensities of 50-150 /spl mu/A, at a pulse width of 0.2 ms and at frequencies of 30-40 Hz and occurred after delay of 8-40 s. This study suggests that focal microstimulation of the sacral spinal cord might be useful in eliciting penile erectile activity in patients with spinal cord injury.