A Case of Consciousness Disturbance Resulting from Severe Hypothyroidism due to Chronic Thyroiditis and Excess Iodine Absorption
A Case of Consciousness Disturbance Resulting from Severe Hypothyroidism due to Chronic Thyroiditis and Excess Iodine Absorption
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DOI：
10.2169/internalmedicine.50.5599
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发表时间：
2011-01-01
影响因子：
1.2
通讯作者：
Tanaka, Hiroshi
中科院分区：
文献类型：
--
作者：
Hayashi, Masayuki;Onodera, Kazunari;Tanaka, Hiroshi
一名82岁的日本男性因经皮吸收用于治疗糖尿病坏疽的含碘软膏中的碘引发重度甲状腺功能减退症而出现意识障碍。实验室数据显示尿碘浓度极高，慢性甲状腺炎引起的甲状腺功能减退。过量的碘摄入也会引起甲状腺功能减退。碘中毒或桥本脑病不太可能引起意识障碍。患者在停止使用软膏并开始甲状腺激素治疗后恢复意识。我们认为意识障碍是由于慢性甲状腺炎和过量碘吸收引起的严重甲减所致。
An 82-year-old Japanese man had consciousness disturbance due to severe hypothyroidism triggered by percutaneous absorption of iodine from an iodine-containing ointment used in diabetic gangrene treatment. Laboratory data revealed extremely high urinary iodine concentrations, and chronic thyroiditis-induced hypothyroidism. Excess iodine intake can also cause hypothyroidism. It was unlikely that iodine intoxication or Hashimoto's encephalopathy had caused the consciousness disturbance. The patient regained consciousness after discontinuing the use of the ointment and commencing thyroid hormone therapy. We conclude that consciousness disturbance resulted from severe hypothyroidism caused by chronic thyroiditis and excess iodine absorption.