Effects of dietary anthocyanins on tocopherols and lipids in rats
Effects of dietary anthocyanins on tocopherols and lipids in rats
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DOI：
10.1021/jf025716n
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发表时间：
2002-12-04
影响因子：
6.1
通讯作者：
Vessby, B
中科院分区：
文献类型：
--
作者：
Frank, J;Kamal-Eldin, A;Vessby, B
在Sprague-Dawley品系的生长交配大鼠中，研究了膳食矢车菊素-3-O-葡萄糖苷（M）和黑醋栗[Ribes nigrum]（BC）和接骨木[Sambucus nigra]（EC）浓缩物对血浆和组织中α-（α-T）和γ-生育酚（γ-T）和胆固醇浓度以及肝脏脂质脂肪酸组成的影响。动物喂食补充有2g/kg C3 G、BC或EC的半合成饮食4周。日粮中添加花青素不影响采食量、体重和器官重量。C3 G能显著提高肝、肺组织中生育酚的含量（P < 0.05）。血浆和肝脏中的胆固醇水平不受任何方案的影响。C3 G和BC降低了肝脏中饱和脂肪酸的相对含量（P < 0.05），BC降低了22：6 + 24：0和EC的20：3/20：4 n-6比值（P < 0.05）。总之，饮食C3 G，BC和EC似乎对肝脏中的胆固醇水平和脂肪酸模式影响不大，但似乎能够在健康的生长大鼠中节省维生素E。
The effects of dietary cyanidin-3-O-glucoside (M) and concentrates from blackcurrant [Ribes nigrum] (BC) and elderberry [Sambucus nigra] (EC) on plasma and tissue concentrations of alpha- (alpha-T) and gamma-tocopherol (gamma-T) and cholesterol, as well as the fatty acid composition of the liver lipids were investigated in growing, mate rats of the Sprague-Dawley strain. Animals were fed semisynthetic diets supplemented with 2 g/kg C3G, BC, or EC for 4 weeks. Dietary anthocyanins did not affect feed intake, body weight, and organ weights. C3G elevated the concentrations of tocopherols in the liver and lungs (P < 0.05). Cholesterol levels in plasma and liver were not affected by any of the regimens. C3G and BC reduced the relative amount of saturated fatty acids in the liver (P < 0.05) BC also lowered the percentage of 22:6 + 24:0 and EC the ratio of 20:3/20:4 n-6 (P < 0.05). In conclusion, dietary C3G, BC, and EC appear to have little effect on cholesterol levels and the fatty acid pattern in the liver but seem to be capable of sparing vitamin E in healthy, growing rats.