EFFECTS OF METHYLPHENIDATE ON AVOIDANCE-LEARNING IN AGED RAT
EFFECTS OF METHYLPHENIDATE ON AVOIDANCE-LEARNING IN AGED RAT
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DOI：
10.1080/00221309.1977.9920823
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发表时间：
1977-01-01
影响因子：
2.5
通讯作者：
ROWLEY, VN
中科院分区：
文献类型：
--
作者：
GLOCK, D;GAURON, EF;ROWLEY, VN
对20只22至26月龄的Sprague道利大鼠皮下注射4.5 mg/kg哌甲酯或蒸馏水。单次注射后12分钟，大鼠开始90次回避条件反射试验。药物动物比对照动物做出了更正确的反应。结果表明，使用哌醋甲酯在老年大鼠改善回避学习。
Twenty Sprague Dawley rats, aged 22 to 26 months were given subcutaneous injections of 4.5 mg/kg methylphenidate or distilled water. Twelve minutes after the single injection was given, rats began 90 trials of avoidance conditioning. Drug animals made significantly more correct responses than did the control animals. Results indicate that use of methylphenidate in aged rats improved avoidance learning.