Multifunctional supramolecular vesicles based on the complex of ferrocenecarboxylic acid capped pillar[5]arene and a galactose derivative for targeted drug delivery
Multifunctional supramolecular vesicles based on the complex of ferrocenecarboxylic acid capped pillar[5]arene and a galactose derivative for targeted drug delivery
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基于二茂铁羧酸封端的柱[5]芳烃和半乳糖衍生物复合物的多功能超分子囊泡，用于靶向药物递送
DOI：
10.1039/c6cc03637f
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发表时间：
2016-01-01
影响因子：
4.9
通讯作者：
Pei, Zhichao
中科院分区：
文献类型：
--
作者：
Chang, Yincheng;Hou, Chenxi;Pei, Zhichao
基于二茂铁羧酸封端的柱[5]芳烃与半乳糖衍生物的主客体络合作用，构建了具有双重响应性的超分子囊泡，并分别以二茂铁羧酸单元和半乳糖单元为靶向单元，实现了对肿瘤细胞的靶向作用。这项工作为构建多功能纳米载体用于靶向药物递送提供了一个很好的例子。
Supramolecular vesicles based on the host-guest complexation of ferrocenecarboxylic acid capped pillar[5]arene and a galactose derivative have been constructed, which showed dual-responsiveness and cancer cells targetability resulting from its ferrocenecarboxylic acid units and galactose units, respectively. This work provides a good example for the construction of multifunctional nanocarriers for targeted drug delivery.