Template-Free Synthesis of Mesoporous Polymers for Highly Selective Enrichment of Glycopeptides
Template-Free Synthesis of Mesoporous Polymers for Highly Selective Enrichment of Glycopeptides
复制标题
用于高选择性富集糖肽的介孔聚合物的无模板合成
DOI：
10.1021/acsmacrolett.5b00235
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发表时间：
2015-05-01
影响因子：
7.015
通讯作者：
Dai, Sheng
中科院分区：
文献类型：
--
作者：
Jin, Tian;Xiong, Zhichao;Dai, Sheng
提出了一种简单的无模板策略，用于合成具有吸引孔率，含氮功能和固有亲水骨架的介孔酚醛聚合物。所得聚合物具有较高的BET表面积(548 m（2) g(-1)）和介孔尺寸（13 nm），具有优越的糖肽捕获性能，从而揭示了介孔聚合物在高选择性糖肽富集方面的潜在应用。这种通用的捕获方案可能为糖蛋白组的发展开辟新的机会。
A facile template-free strategy for the synthesis of mesoporous phenolic polymers with attractive porosities, nitrogen-containing functionalities, and intrinsic hydrophilic skeletons is presented. The resultant polymer has a high BET surface area (548 m(2) g(-1)) and mesopore size (13 nm) and exhibits superior glycopeptide-capturing performance, thus, revealing the potential application of mesoporous polymers in highly selective glycopeptide enrichment. This general capture protocol may open up new opportunities for the development of glycoproteomes.