A nanocomposite approach to develop biodegradable thermogels exhibiting excellent cell-compatibility for injectable cell delivery

A nanocomposite approach to develop biodegradable thermogels exhibiting excellent cell-compatibility for injectable cell delivery
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DOI:
10.1039/c4bm00074a
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发表时间:
2014-01-01
影响因子:
6.6
通讯作者:
Nagahama, Koji
Nagahama, Koji
中科院分区:
工程技术2区
文献类型:
--
作者:
Oyama, Naho;Minami, Hiromasa;Nagahama, Koji

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通过可生物降解的聚(丙交酯-共-乙交酯)-b-聚(乙二醇)-b-聚(丙交酯-共-乙交酯)共聚物胶束和粘土纳米片的协同自组装,开发了一类具有优异细胞相容性的新型可注射纳米复合热凝胶。本研究对建立可注射的细胞递送技术具有一定的参考价值。
A new class of injectable nanocomposite thermogels having excellent cell-compatibility were developed through cooperative self-assembly of biodegradable poly(lactide-co-glycolide)-b-poly(ethylene glycol)-b-poly(lactide-co-glycolide) copolymer micelles and clay nanosheets for effective cell delivery. This study will be valuable for the establishment of injectable cell delivery technology.