Diffusion-Weighted Breast Magnetic Resonance Imaging: A Semiautomated Voxel Selection Technique Improves Interreader Reproducibility of Apparent Diffusion Coefficient Measurements.
Diffusion-Weighted Breast Magnetic Resonance Imaging: A Semiautomated Voxel Selection Technique Improves Interreader Reproducibility of Apparent Diffusion Coefficient Measurements.
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DOI：
10.1097/rct.0000000000000372
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发表时间：
2016-05
影响因子：
1.3
通讯作者：
Partridge SC
中科院分区：
文献类型：
--
作者：
Rahbar H;Kurland BF;Olson ML;Kitsch AE;Scheel JR;Chai X;Usoro J;Lehman CD;Partridge SC
确定半自动体素选择技术是否可以提高乳腺表观扩散系数 (ADC) 测量的读者间再现性。三位读者回顾性地对 26 名女性的 31 个乳腺病变（16 个恶性，15 个良性）和对侧正常组织进行了 ADC 测量，其中包括无辅助（手动方法）和半自动软件工具的辅助，该工具排除低于动态指定信号强度阈值的体素。通过 Bland-Altman 分析和一致性相关系数 (CCC) 评估每种技术的读者之间的再现性。与手动方法相比，读者使用半自动工具测量的病变 ADC 之间的差异更小。使用半自动病变工具时，每对读取器的 CCC 更大（平均 CCC 差异 = 0.11；CI = 0.04–0.26）。对于正常组织，读者一致性低于病变组织，并且基于软件工具没有差异（平均 CCC 差异 = 0.00；95% CI= -0.14–0.13）。半自动体素选择工具可以提高乳腺病变 ADC 测量的读者间再现性。
To determine whether a semi-automated voxel selection technique improves inter-reader reproducibility for breast apparent diffusion coefficient (ADC) measurements. Three readers retrospectively performed ADC measurements of 31 breast lesions (16 malignant, 15 benign) and contralateral normal tissue in 26 women both unassisted (manual method) and assisted by a semi-automated software tool that excludes voxels below a dynamically specified signal intensity threshold. Reproducibility between readers for each technique was assessed by Bland-Altman analysis and concordance correlation coefficients (CCCs). Differences between readers’ measured ADCs of lesions were smaller with the semi-automated tool versus the manual method. CCCs for each reader pair were greater with the semi-automated tool for lesions (mean CCC difference= 0.11; CI= 0.04–0.26). For normal tissue, reader agreement was lower than for lesions, and did not differ based on software tools (mean CCC difference= 0.00; 95% CI= −0.14–0.13). A semi-automated voxel selection tool can improve inter-reader reproducibility of breast lesion ADC measures.