Free-Standing Biodegradable Poly(lactic acid) Nanosheet for Sealing Operations in Surgery
Free-Standing Biodegradable Poly(lactic acid) Nanosheet for Sealing Operations in Surgery
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DOI：
10.1002/adma.200901035
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发表时间：
2009-11-20
影响因子：
29.4
通讯作者：
Takeoka, Shinji
中科院分区：
文献类型：
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作者：
Okamura, Yosuke;Kabata, Koki;Takeoka, Shinji
由聚L-乳酸(PLLA)组成的可自由站立的可生物降解纳米片作为一种新型的不需要粘合剂的创面敷料，对胃切口处具有良好的封闭效果，并且PLLA纳米片诱导的伤口修复既没有疤痕，也没有组织粘连。因此，这种材料可能是一种理想的替代手术中使用缝合/结扎的传统组织修复方法。
A free-standing biodegradable nanosheet composed of poly(L-lactic acid) (PLLA) was shown to have excellent sealing efficacy for a gastric incision as a novel wound dressing material that did not require adhesive agents, and the PLLA nanosheet-induced wound repair showed neither scars nor tissue adhesion. This material may, therefore, be an ideal alternative to conventional tissue repairing procedures using suture/ligation in surgery.