Applications of optical resonance to biological imaging and label-free protein microarrays.

Applications of optical resonance to biological imaging and label-free protein microarrays.
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光学共振在生物成像和无标记蛋白质微阵列中的应用。

DOI：
10.1109/iembs.2008.4649744
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发表时间：
2008
期刊：
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
影响因子：
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通讯作者：
DeLisi,C
DeLisi,C
中科院分区：
--
文献类型：
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作者：
Unlü,MSelim;Ozkumur,IE;Needham,J;Bergstein,DA;Goldberg,BB;Yalcin,A;Spuhler,P;Irani,R;DeLisi,C

文献摘要

相似文献

我们提出了基于光学共振和干涉的生物成像和传感方法。在荧光显微镜中，我们的纳米级成像能力可以揭示固体表面上DNA、DNA-蛋白质复合物和聚合物涂层的构象变化。分层基板上的干扰测量产生一个无标记的传感平台的蛋白质结合在一个高通量的微阵列格式。
We present biological imaging and sensing methods based on optical resonance and interference. In fluorescence microscopy, our nanoscale imaging capability sheds light onto conformational changes of DNA, DNA-protein complexes and polymer coatings on a solid surface. Interference measurements on a layered substrate yield a label-free sensing platform for protein binding in a high-throughput micro-array format.