Physical activity and sedentary behavior in patients with systemic lupus erythematosus and rheumatoid arthritis.
Physical activity and sedentary behavior in patients with systemic lupus erythematosus and rheumatoid arthritis.
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DOI：
10.2147/oarrr.s148376
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发表时间：
2017
期刊：
影响因子：
--
通讯作者：
Hanly JG
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文献类型：
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作者：
Legge A;Blanchard C;Hanly JG
系统性红斑狼疮（SLE）和类风湿性关节炎（RA）患者患心血管疾病（CVD）的风险增加。由于久坐行为和缺乏体力活动是已知的心血管危险因素，我们比较了SLE患者、RA患者和健康对照组之间的习惯性活动。在这项横断面研究中，从2013年4月至2014年12月在某学术医疗中心的风湿病诊所招募RA和SLE患者。在同一时期，通过当地广告招募健康对照参与者。使用连续7天醒着时佩戴的三轴加速度计测量习惯性活动。记录SLE、RA和健康参与者每天久坐、轻度和中度剧烈身体活动（MVPA）的分钟数，并使用方差分析（ANOVA）对其进行比较。共有59名参与者被纳入分析：20名SLE患者，19名RA患者和20名健康对照。SLE组和RA组的疾病活动都是静止的。所有三组都表现出高久坐行为（所有参与者的平均久坐时间：10.1±1.3小时/天；76.4%的总磨损时间）。SLE、RA和健康参与者在久坐行为（p=0.80）或轻度活动（p=0.17）的时间上没有显著差异。与对照组（64.9±22.4）相比，SLE（34.5±22.7,p<0.001）和RA（41.5±21.3,p=0.005）患者的总MVPA（平均±SD，分钟/天）显著降低。SLE和RA患者尽管病情控制良好，但MVPA仍未达到最佳水平。鉴于心血管疾病风险的增加，需要有效的干预措施来改善这两个人群的习惯性体育活动水平。
Patients with systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) are at increased risk of cardiovascular disease (CVD). As sedentary behavior and lack of physical activity are known cardiovascular risk factors, we compared habitual activity between SLE patients, RA patients, and healthy control participants. For this cross-sectional study, RA and SLE patients were recruited from rheumatology clinics at an academic medical center from April 2013 to December 2014. Healthy control participants were recruited through local advertising during the same time period. Habitual activity was measured using a triaxial accelerometer worn during waking hours for 7 consecutive days. Minutes per day of sedentary, light, and moderate–vigorous physical activity (MVPA) were recorded and compared between SLE, RA, and healthy participants using ANOVA. There were 59 participants included in the analysis: 20 SLE patients, 19 RA patients, and 20 healthy controls. Disease activity was quiescent in both the SLE and RA groups. All three groups demonstrated high sedentary behavior (mean ± SD sedentary time for all participants: 10.1±1.3 hours/day; 76.4% total wear time). There were no significant differences between SLE, RA, and healthy participants in time spent in sedentary behavior (p=0.80) or light activity (p=0.17). Total MVPA (mean ± SD, minutes/day) was significantly lower in SLE (34.5±22.7; p<0.001) and RA (41.5±21.3; p=0.005) patients compared to controls (64.9±22.4). SLE and RA patients demonstrate suboptimal MVPA despite well-controlled disease. Given their increased CVD risk, effective interventions are required to improve habitual physical activity levels in both populations.