Biofunctionalization of polyelectrolyte microcapsules with biotinylated polyethylene glycol-grafted liposomes.
Biofunctionalization of polyelectrolyte microcapsules with biotinylated polyethylene glycol-grafted liposomes.
复制标题
聚电解质微胶囊与生物素化聚乙二醇接枝脂质体的生物功能化。
作者：
Jie Gao;U. Reibetanz;S. Venkatraman;B. Neu
Hollow polyelectrolyte microcapsules (PEMC) are prepared using layer-by-layer self-assembly of polyelectrolytes on melamine formaldehyde templates, followed by template dissolution, and subsequent coating with biotinylated polyethylene glycol-grafted liposomes. These potential site-specific carrier systems show a high specificity for NeutrAvidin binding and a strong resistance against unspecific protein binding. It is concluded that this design with NeutrAvidin as the outermost layer of such capsules provides an ideal platform for the biofunctionalization of PEMC as drug delivery systems or as artificial cell-like structures for biomimetic studies.
影响因子：
4.7
作者：
Lackey, CA;Murthy, N;Stayton, PS
通讯作者：
Stayton, PS
影响因子：
4.9
作者：
Ai, H;Pink, JJ;Gao, JM
通讯作者：
Gao, JM