Synthesis of (R)-(+)-Hippospongic Acid A, a Triterpene Isolated from the Marine Sponge, Hippospongia sp.

Synthesis of (R)-(+)-Hippospongic Acid A, a Triterpene Isolated from the Marine Sponge, Hippospongia sp.
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(R)-( )-Hipposponic Acid A(一种从海洋海绵 Hippospongia sp. 中分离出来的三萜)的合成。

DOI:
10.1271/bbb.65.2569
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发表时间:
2001
期刊:
Bioscience, biotechnology and biochemistry
影响因子:
--
通讯作者:
K. Mori
K. Mori
中科院分区:
--
文献类型:
--
作者:
M. Ichihashi;H. Takikawa;K. Mori

文献摘要

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Hipposponic Acid A (1) 是海洋海绵 Hippospongia sp. 的一种三萜代谢物,对海星胚胎的原肠胚形成具有抑制活性。以酶动力学拆分为关键步骤合成了(R)-(+)-1。
Hippospongic acid A (1) is a triterpene metabolite of the marine sponge, Hippospongia sp., with inhibitory activity against the gastrulation of starfish embryos. (R)-(+)-1 was synthesized by employing enzymatic kinetic resolution as the key step.