Malaria Prevalence in Endemic Districts of Bangladesh
Malaria Prevalence in Endemic Districts of Bangladesh
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DOI：
10.1371/journal.pone.0006737
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发表时间：
2009-08-25
期刊：
影响因子：
3.7
通讯作者：
Haque, Rashidul
中科院分区：
文献类型：
--
作者：
Haque, Ubydul;Ahmed, Syed Masud;Haque, Rashidul
背景：自1971年孟加拉国禁用滴滴涕以来，疟疾病例稳步增加。在孟加拉国东南部和东北部的13个地区，疟疾仍然是一个主要的健康问题。目前，国家疟疾防治方案主要由全球防治艾滋病、结核病和疟疾基金支助，提供干预措施，包括在社区一级进行宣传、分发驱虫蚊帐、采用快速诊断测试和复方蒿甲醚综合疗法。因此，必须收集关于疟疾流行率和其他疟疾指标的基线数据，以评估干预措施的效力，并使预防和控制工作合理化。本研究的目的是获得这一基线的疟疾和蚊帐使用的流行率在13个疟疾流行区的Banglades.Methods和主要调查结果：在2007年，BRAC和ICDDR，B进行了疟疾流行调查，在13个疟疾流行区的孟加拉国。采用多阶段整群抽样技术，采集血样9750份。快速诊断试验（RDT）用于诊断疟疾。13个疟疾流行区的加权平均发病率为3.97%。东南部5个县的加权平均疟疾流行率为6.00%，东北部8个县的加权平均疟疾流行率为0.40%。据观察，疟疾流行率最高的是哈格拉查里区。恶性疟原虫感染占绝大多数（90.18%）。东南部五个县的疟疾发病率为2.94%。东北部8个区的发病率为0.07%。结论和意义：孟加拉国是以恶性疟原虫为优势寄生虫的低度地方性疟疾。孟加拉国东北部五个地区的疟疾情况尤其值得紧急关注。基线疟疾流行率的详细地图和收集的数据摘要沿着以补充资料的形式提供了调查结果全文
Background: Following the 1971 ban of DDT in Bangladesh, malaria cases have increased steadily. Malaria persists as a major health problem in the thirteen south-eastern and north-eastern districts of Bangladesh. At present the national malaria control program, largely supported by the Global Fund for AIDS, Tuberculosis and Malaria (GFATM), provides interventions including advocacy at community level, Insecticide Treated Net (ITN) distribution, introduction of Rapid Diagnostic Tests (RDT) and combination therapy with Coartem. It is imperative, therefore, that baseline data on malaria prevalence and other malaria indicators are collected to assess the effectiveness of the interventions and rationalize the prevention and control efforts. The objective of this study was to obtain this baseline on the prevalence of malaria and bed net use in the thirteen malaria endemic districts of Bangladesh.Methods and Principal Findings: In 2007, BRAC and ICDDR, B carried out a malaria prevalence survey in thirteen malaria endemic districts of Bangladesh. A multi-stage cluster sampling technique was used and 9750 blood samples were collected. Rapid Diagnostic Tests (RDT) were used for the diagnosis of malaria. The weighted average malaria prevalence in the thirteen endemic districts was 3.97%. In five south-eastern districts weighted average malaria prevalence rate was 6.00% and in the eight north-eastern districts weighted average malaria prevalence rate was (0.40%). The highest malaria prevalence was observed in Khagrachari district. The majority of the cases (90.18%) were P. falciparum infections. Malaria morbidity rates in five south-eastern districts was 2.94%. In eight north-eastern districts, morbidity was 0.07%.Conclusion and Significance: Bangladesh has hypoendemic malaria with P. falciparum the dominant parasite species. The malaria situation in the five north-eastern districts of Bangladesh in particular warrants urgent attention. Detailed maps of the baseline malaria prevalence and summaries of the data collected are provided along with the survey results in full, in a supplemental information