STUDIES IN PREBIOTIC SYNTHESIS .6. SYNTHESIS OF PURINE NUCLEOSIDES
STUDIES IN PREBIOTIC SYNTHESIS .6. SYNTHESIS OF PURINE NUCLEOSIDES
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DOI：
10.1016/0022-2836(72)90383-x
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发表时间：
1972-01-01
影响因子：
5.6
通讯作者：
ORGEL, LE
中科院分区：
文献类型：
--
作者：
FULLER, WD;SANCHEZ, RA;ORGEL, LE
The isomers of 6-ribosylaminopurine (N6-ribosyladenine) are formed in up to 74% yield when a dry mixture of adenine and ribose is heated. Under these conditions ribose also reacts with the primary amine group of adenosine, guanosine and probably guanine to form the corresponding ribosylaminopurines, while hypoxanthine fails to react. In the presence of Mg2+and inorganic polyphosphates the natural nucleosides are also formed. Maximum yields of β-inosine, β-adenosine and β-guanosine were 8%, 4% and 9%, respectively.
