Estradiol is concentrated in tyrosine hydroxylase-containing neurons of the hypothalamus.
Estradiol is concentrated in tyrosine hydroxylase-containing neurons of the hypothalamus.
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雌二醇集中在下丘脑含有酪氨酸羟化酶的神经元中。
DOI：
10.1126/science.6141639
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发表时间：
1984
期刊：
影响因子：
--
通讯作者：
Sar,M
中科院分区：
文献类型：
--
作者：
Sar,M
通过放射自显影和免疫组织化学的联合技术显示[3H]雌二醇在大鼠脑中含有酪氨酸羟化酶的神经元中的定位。 [3H]雌二醇集中在弓状核、下丘脑室周核和未定带中含有酪氨酸羟化酶的神经元的细胞核中。这些结果表明雌二醇直接作用于结节漏斗系统和下丘脑间系统的产生多巴胺的神经元。
Localization of [3H]estradiol in tyrosine hydroxylase-containing neurons of rat brain was shown by a combined technique of autoradiography and immunohistochemistry. [3H]Estradiol was concentrated in the nuclei of tyrosine hydroxylase-containing neurons in the nucleus arcuatus, nucleus periventricularis hypothalami, and the zona incerta. These results suggest that estradiol acts directly on dopamine-producing neurons of the tuberoinfundibular system and incertohypothalamic system.