[Colonization of Candida species and efficacy of miconazole gel in overdenture wearers].
[Colonization of Candida species and efficacy of miconazole gel in overdenture wearers].
复制标题
[念珠菌属的定植和咪康唑凝胶对覆盖义齿佩戴者的功效]。
DOI：
10.2186/jjps.52.99
复制
发表时间：
2008
期刊：
影响因子：
--
通讯作者：
T. Ichikawa
中科院分区：
文献类型：
--
作者：
Y. Yoshijima;T. Ichikawa
目的
目的：观察咪康唑凝胶对覆盖义齿患者念珠菌定植的抑制作用。
方法
受试者为26名覆盖义齿佩戴者。达克宁凝胶的用法如下：A组：达克宁凝胶1.5 g，每日4次，共1周; B组：达克宁凝胶0.5 g，每日4次，共1周。作为筛选试验，检查义齿菌斑、牙菌斑和咽粘膜中的念珠菌属。在咪康唑凝胶应用于念珠菌阳性受试者之前和之后，对念珠菌属、细菌总数和口腔链球菌进行计数。
结果
26例受检者中18例检出念珠菌，其中基牙基托周围念珠菌检出率较高。所有念珠菌对咪康唑凝胶均敏感。咪康唑凝胶应用于13例受试者。使用咪康唑凝胶1周后念珠菌数量明显减少，副作用少。
结论
结论咪康唑凝胶是一种安全有效的口腔护理方法，可有效控制覆盖义齿患者的菌斑。
PURPOSE
Preliminarily to examine the efficacy of miconazole gel at inhibiting colonization of Candida species in overdenture wearers.
METHODS
The subjects were 26 overdenture wearers. Miconazole gel was used with the following directions: group A was prescribed miconazole gel 1.5 g 4 times daily for 1 week, group B was prescribed miconazole gel 0.5 g 4 times daily for 1 week. As a screening test, Candida species were examined in denture plaque, dental plaque, and pharyngeal mucosa. The number of Candida species, total bacteria, and oral streptococci were counted before and after application of miconazole gel to Candida-positive subjects.
RESULTS
Candida species were detected in 18 of 26 subjects and high incidence was found around the abutments under the denture base. All Candida species were sensitive to miconazole gel. Miconazole gel was applied to 13 subjects. The number of Candida was reduced after 1-week use of miconazole gel with few side effects during the application.
CONCLUSION
It is suggested that miconazole gel will be an effective and safe method for oral care and denture plaque control in overdenture wearers.