3 NEW SESQUITERPENE HYDROQUINONES FROM MARINE ORIGIN

3 NEW SESQUITERPENE HYDROQUINONES FROM MARINE ORIGIN
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DOI:
10.1016/s0040-4020(01)86712-0
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发表时间:
1994-04-04
期刊:
影响因子:
2.1
通讯作者:
HIZI, A
HIZI, A
中科院分区:
化学3区
文献类型:
--
作者:
TALPIR, R;RUDI, A;HIZI, A

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从紫球藻(Peyssonnelia sp.)中分离得到3个新的倍半萜对苯二酚A和B(5和6)和水葫芦酚(7)。还有海绵。这三个化合物的结构主要通过核磁共振确定。Peyssonol A(5)是首次报道的溴倍半萜对苯二酚。在一项抑制人类免疫缺陷病毒(HIV)逆转录酶的初步测试中发现了几种新化合物。
Three new sesquiterpene hydroquinones peyssonol A and B (5 and 6) and hyatellaquinone (7) have been isolated from the alga Peyssonnelia sp. and the sponge Hyatella intestinalis. The structure of the three compounds was determined mainly by NMR measurements. Peyssonol A (5) is the first reported bromo sesquiterpene hydroquinone. Several of the new compounds were found in a preliminary test to inhibit the reverse transcriptase of human immunodeficiency virus (HIV).