In vitro corrosion of magnesium alloy AZ31 — a synergetic influence of glucose and Tris
In vitro corrosion of magnesium alloy AZ31 — a synergetic influence of glucose and Tris
复制标题
镁合金 AZ31 的体外腐蚀 — 葡萄糖和 Tris 的协同影响
DOI：
10.1007/s11706-018-0424-1
复制
发表时间：
2018
影响因子：
2.7
通讯作者：
刘青云
中科院分区：
文献类型：
--
作者：
李令玉;Bin LIU;曾荣昌;李硕琦;张芬;邹玉红;Hongwei George Jiang;陈晓博;关绍康;刘青云
可生物降解镁合金在生物医学领域的应用引起了人们极大的兴趣。通过具有成本效益的体内评价准确预测镁合金的体内降解需要后者在接近生理环境的环境中进行。然而，葡萄糖和缓冲剂在调节镁合金体内降解性能中的作用尚未阐明。本文采用析氢、pH监测和电化学测试等方法研究了AZ 31镁合金的降解行为。结果表明，葡萄糖对AZ 31镁合金在无缓冲盐溶液中的降解具有浓度依赖性。低浓度（1.0 g/L）葡萄糖的存在降低了镁合金AZ 31的腐蚀速率，而2.0和3.0 g/L葡萄糖的存在则加速了镁合金在盐溶液中的腐蚀速率。在Tris缓冲盐溶液中，葡萄糖的加入增加了AZ 31合金的pH值，促进了AZ 31合金的点蚀或全面腐蚀。该研究为了解镁合金在缓冲液和葡萄糖溶液中的生物腐蚀提供了一个新的视角。
Biodegradable Mg alloys have generated great interest for biomedical applications. Accurate predictions of in vivo degradation of Mg alloys through cost-effective in vivo evaluations require the latter to be conducted in an environment close to that of physiological scenarios. However, the roles of glucose and buffering agents in regulating the in vivo degradation performance of Mg alloys has not been elucidated. Herein, degradation behavior of AZ31 alloy is investigated by hydrogen evolution measurements, pH monitoring and electrochemical tests. Results indicate that glucose plays a content-dependent role in degradation of AZ31 alloy in buffer-free saline solution. The presence of a low concentration of glucose, i.e. 1.0 g/L, decreases the corrosion rate of Mg alloy AZ31, whereas the presence of 2.0 and 3.0 g/L glucose accelerates the corrosion rate during long term immersion in saline solution. In terms of Tris-buffered saline solution, the addition of glucose increases pH value and promotes pitting corrosion or general corrosion of AZ31 alloy. This study provides a novel perspective to understand the bio-corrosion of Mg alloys in buffering agents and glucose containing solutions.