Fast Synthesis of Complex Enantiopure Heterocyclic Scaffolds by a Tandem Sequence of Simple Transformations on α-Hydroxyaldehydes
Fast Synthesis of Complex Enantiopure Heterocyclic Scaffolds by a Tandem Sequence of Simple Transformations on α-Hydroxyaldehydes
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DOI：
10.1002/chem.201301712
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发表时间：
2013-07-08
影响因子：
4.3
通讯作者：
Beau, Jean-Marie
中科院分区：
文献类型：
--
作者：
Cannillo, Alexandre;Norsikian, Stephanie;Beau, Jean-Marie
两个串联比一个快！由Petasis氨基醇合成引发的由硼酸、二烯丙基胺和α-羟基醛（包括游离醛糖）的适当顺序的反应导致快速构建复杂的对映体纯结构（参见方案）。
Two tandems are faster than one! Properly sequenced reactions initiated by the Petasis aminoalcohol synthesis from boronic acids, diallylamine, and α‐hydroxyaldehydes, including free aldoses, leads to rapid construction of complex enantiopure structures (see scheme).