Prediction of protein folding rates from the amino acid sequence-predicted secondary structure
Prediction of protein folding rates from the amino acid sequence-predicted secondary structure
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DOI：
10.1073/pnas.0402659101
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发表时间：
2004-06-15
影响因子：
11.1
通讯作者：
Finkelstein, AV
中科院分区：
文献类型：
--
作者：
Ivankov, DN;Finkelstein, AV
我们提出了一种预测蛋白质折叠率的方法，仅从它们的氨基酸序列，或者更确切地说，从它们的链长度和螺旋度预测它们的序列。对目前研究的64种“双态”和“多态”蛋白（包括两种人工多肽），该方法与实验的相关度达到82%。
We present a method for predicting folding rates of proteins from their amino acid sequences only, or rather, from their chain lengths and their helicity predicted from their sequences. The method achieves 82% correlation with experiment over all 64 "two-state" and "multistate" proteins (including two artificial peptides) studied up to now.